Epilepsy Related Work

  • Introduction
  • Publication
  • Contact Us
  1. Qifu Li, Cheng  Luo, Tianhua Yang, Zhiping Yao, Li He, Ling Liu, Hongru Xu, Qqiyong Gong,  Dezhong Yao, Dong Zhou*. EEG-fMRI  study on the interictal and ictal generalized spike-wave discharges in patient  with childhood absence  epilepsy. Epilepsy Research.2009,87:160-168.

  2. Cheng Luo, Zhiping Yao, Qifu Li, Xu Lei, Dong Zhou, Yun Qin,  Yang Xia, Yongxiu Lai, Qiyong Gong, Dezhong Yao. Imaging foci of epileptic  discharges from simultaneous EEG and fMRI using the canonical HRF. Epilepsy Research.2010,  91(2-3): 133-142

  3. Cheng Luo,  Zhiping Yao, Qifu Li, Xu Lei, Dong Zhou, Yun Qin, Yang Xia,Yongxiu Lai, Qiyong  Gong, Dezhong Yao*. Imaging foci of epileptic discharges from simultaneous EEG  and fMRI using the canonical HRF. Epilepsy Res,2010.91:133-42.

  4. Cheng Luo, Qifu  Li, Yongxiu Lai, Yang Xia, Yun Qin, Wei Liao, Shasha Li, Dong Zhou, Dezhong Yao*,  Qiyong Gong. Altered Functional Connectivity in Default Mode Network in Absence  Epilepsy interictal duration without IED: A Resting-state fMRI Study. Human  Brain Mapping.2011,32(3):438-449.

  5. Cheng Luo, Yang  Xia, Qifu Li, Kaiqing Xue, Yongxiu Lai, Qiyong Gong, Dong Zhou*, Dezhong  Yao*. Diffusion and volumetry abnormalities in  subcortical nuclei of patients with absence seizures. Epilepsia. 2011, 52(6):1092-1099.

  6. Cheng Luo, Qifu  Li, Yang Xia, Xu Lei, Kaiqing Xue, Zhiping Yao, Youxiu Lai, Wei Liao, Dong  Zhou, Pedro A Valdes‐Sosa, Qiyong Gong, Dezhong Yao. Resting State Basal Ganglia Network in  Idiopathic generalized epilepsy. Human Brain Mapping.2012,33: 1279-1294.

  7. Cheng Luo, Qifu  Li, Yang Xia, Xu Lei, Kaiqing Xue, Zhiping Yao, Youxiu Lai, Wei Liao, Dong  Zhou, Pedro A Valdes‐Sosa, Qiyong Gong, Dezhong Yao*. Resting State Basal Ganglia Network in  Idiopathic generalized epilepsy. Human Brain Mapping.2012,33: 1279-1294.

  8. Tianhua Yang,  Zhiwei Guo, Cheng Luo, Qifu Li, Bo Yan, Ling Liu, Qiyong Gong, Dezhong Yao,  Dong Zhou*, White Matter Impairment in the Basal Ganglia-Thalamocortical  Circuit of Drug-Naive Childhood Absence Epilepsy, Epilepsy Res  2012(99):267-273.

  9. Tianhua Yang,  Cheng Luo, Qifu Li, Zhiwei Guo, Ling Liu, Qiyong Gong, Dezhong Yao, Dong Zhou*.  Altered resting-state connectivity during interictal generalized spike-wave  discharges in drug-naïve childhood absence epilepsy. Human Brain  Mapping.2013,34(8):1761-1767.

  10. Cheng Luo, Tianhua Yang, Shipeng Tu, Jiayan Deng,  Dongbo Liu, Qifu Li, Li Dong, Ilan Goldberg, Qiyong Gong, Dan Zhang, Dongmei  An, Dong Zhou*, Dezhong Yao*, Altered Intrinsic Functional Connectivity of  Salience Network in Childhood Absence Epilepsy, Journal of the Neurological  Sciences. 2014, 339:189-195.

  11. Kaiqing Xue, Cheng Luo, Dan Zhang, Tianhua Yang,  Jianfu Li, Diankun Gong, Long Chen, Yasser Iturria Medina, Jean Gotman, Dong  Zhou, Dezhong Yao*, Diffusion Tensor Tractography RevealsDisrupted Structural  Connectivity in Childhood Absence Epilepsy, Epilepsy Research.  2014,108(1):128-138

  12. Mingming Chen, Daqing Guo*, Tiebin Wang, Wei Jing,  Yang Xia, Peng Xu, Cheng Luo, Pedro A Valdes-Sosa, Dezhong Yao*, Bidirectional  Control of Absence Seizures by the Basal Ganglia: A Computational Evidence.  PLoS Computational Biology, 2014, 10(3):e1003495.

  13. Qifu Li, Weifang Cao, Xiaoping Liao, Zhibin Chen,  Tianhua Yang, Qiyong Gong, Dong Zhou*, Cheng Luo*, Dezhong Yao. Altered resting  state functional network connectivity in children absence epilepsy. Journal of  the neurological sciences. 2015.354(1-2):79-85

  14. Pu Wang, Cheng Luo, Li Dong, Yi Bin, Shi Ma,  Dezhong Yao, Fuqiang Guo*. Altered intrinsic brain activity in patients with  familial cortical myoclonic tremor and epilepsy: An amplitude of low-frequency  fluctuation study. J Neurol Sci, 2015.351(1-2),133-139.doi:  10.1016/j.jns.2015.03.005

  15. Cheng Luo*, Yaodan Zhang, Weifang Cao, Yi Huang,  Fei Yang, Jianjun Wang, Shipeng Tu, Xiaoming Wang*, Dezhong Yao*. Altered  Structural and Functional Feature of Striato-Cortical Circuit In Benign  Epilepsy with Centrotemporal Spikes. International journal of neural systems,  2015: 1550027.

  16. Li Dong, Pu Wang, Yi.Bin, Jiayan Deng, Yongjie Li,  Lin Chen, Cheng Luo, Dezhong Yao*. Local Multimodal Serial Analysis for Fusing  EEG-fMRI: A New Method to Study Familial Cortical Myoclonic Tremor and  Epilepsy. Autonomous Mental Development, IEEE Transactions on, 2015c. PP:1-1.

  17. 杨飞, 罗程, 蒋思思, 王晓明, 青少年肌阵挛癫痫脑网络的研究进展. 中华神经科杂志 48 (2015)  620-622

  18. Li Dong,  Cheng Luo*, Yutian Zhu, Changyue Hou, Sisi Jiang, Pu Wang, Bharat B Biswal,  Dezhong Yao. Complex discharge-affecting networks in juvenile myoclonic  epilepsy: A simultaneous EEG-fMRI study. Hum Brain Mapp, 2016. 37(10),  3515-3529.

  19. Sisi  Jiang, Cheng Luo*, Zhixuan Liu, Changyue Hou, Pu Wang,Li Dong, ChengqingZhong,  Yongxiu Lai,Yang Xia.Dezhong Yao. Altered Local Spontaneous Brain Activity in  Juvenile Myoclonic Epilepsy: A Preliminary Resting-State fMRI Study. Neural  Plast.2016: 3547203

  20. Li Dong, Pu Wang, Rui Peng, Sisi Jiang, B  Klugah-Brown, Cheng Luo*, Dezhong Yao*, Altered basal ganglia-cortical functional  connections in frontal lobe epilepsy: A resting-state fMRI study. Epilepsy  Research,2016(128):12-20

  21. Cheng Luo, Fei Yang, Jiayan Deng, Yaodan Zhang,  Changyue Hou, Yue Huang, Weifang Cao, Jianjun Wang, Ruhui Xiao, Nanlin Zeng,  Xiaoming Wang*, Dezhong Yao*, Altered functional and effective connectivity in  anticorrelated intrinsic networks in children with benign childhood epilepsy  with centrotemporal spikes. Medcine. 2016, 95(24) e3831,  http://dx.doi.org/10.1097/MD.0000000000003831

  22. Li Dong, Hechun Li, Zhongqiong He, Sisi Jiang,  Benjamin Klugah-Brown, Lin Chen, Pu Wang, Song Tan, Cheng Luo*, Dezhong Yao*.  Altered local spontaneous activity in frontal lobe epilepsy: a resting-state  functional magnetic resonance imaging study. Brain and Behavior, 2016, 0:1–8.  e00555

  23. Jinan Gong, Xuebin Chang, Sisi Jiang, Benjamin  Klugah-Brown, Song Tan, Dezhong Yao, Cheng. Luo. Microstructural alterations of  white matter in juvenile myoclonic epilepsy. Elsevier, 2017. (Online)

  24. 贾晓燕,叶国凤,蒋思思,何忠琼,罗程,尧德中. 青少年肌阵挛癫痫的小脑半球功能连接分析[J]. 四川精神卫生. 2017, 30(1)

  25. 罗程,贾晓燕,卓丽华,曹卫芳,蒋宇超,蒋思思,尧德中.小脑 非运动功能异常的影像研究进展.四川精神卫生 [J]. 2017, 30(1)

  26. Sisi Jiang, Cheng Luo*, Jinan Gong, Rui Peng, Shuai  Ma, Song Tan, Guofeng Ye, Li Dong, Dezhong Yao*. Aberrant thalamocortical  connectivity in juvenile myoclonic epilepsy The international journal of neural  systems, 2017 (Accepted)

    Epilepsy is the name of a brain  disorder characterized predominantly by recurrent and unpredictable  interruptions of normal brain function, called epileptic seizures. According to  the characteristics of seizures and clinical manifestations, it can be divided  into focal epilepsy and generalized epilepsy. The etiology of epilepsy is  complex and the pathological mechanism is unclear. Over the past two decades ,  the magnetic resonance imaging (MRI) technology and electroencephalogram (EEG) have  been widely used to investigate epilepsy. An increasing number of evidence has  been presented to reveal the potential illness mechanism.

     Using multimodel imaging techniques, our  research group has done a lot of work to study epilepsy and obtained many  excellent achievements. Our work focused on the localization of epileptic foci,  the regulation effects of basal ganglia on epileptic activity and the  alterations of resting-state brain networks in patients with epilepsy. Accumulated  results help us to have a more comprehensive understanding about epilepsy.